Dissecting the role of aberrant DNA methylation in human leukemia

Chronic Myeloid Leukemia (CML) is a myeloproliferative disorder characterized by the genetic translocation t(9;22)(q34;q11.2) encoding for the BCR-ABL fusion oncogene. However, many molecular mechanisms of the disease progression still remain poorly understood. A growing body of evidence suggests th...

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Bibliographic Details
Main Authors: Amabile, Giovanni, Di Ruscio, Annalisa, Müller, Fabian, Welner, Robert S, Yang, Henry, Ebralidze, Alexander K, Zhang, Hong, Levantini, Elena, Qi, Lihua, Martinelli, Giovanni, Brummelkamp, Thijn, Le Beau, Michelle M, Figueroa, Maria E, Bock, Christoph, Tenen, Daniel G
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443494/