Aquaporin-4 autoimmunity

Neuromyelitis optica (NMO) and a related spectrum of inflammatory CNS disorders are unified by detection of a serum autoantibody specific for the aquaporin-4 (AQP4) water channel, which is abundant in astrocytic foot processes. The classic clinical manifestations of NMO are optic neuritis and longit...

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Bibliographic Details
Main Authors: Zekeridou, Anastasia, Lennon, Vanda A.
Format: Online
Language:English
Published: Lippincott Williams & Wilkins 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442096/