Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)

Symptomatic intracranial hemorrhage (sICH) is a known complication following administration of intravenous tissue plasminogen activator (IV tPA) for acute ischemic stroke. sICH results in high rates of death or long-term disability. Our ability to predict its occurrence is important in clinical deci...

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Main Authors:	Marsh, Elisabeth B., Gottesman, Rebecca F., Hillis, Argye E., Urrutia, Victor C., Llinas, Rafael H.
Format:	Online
Language:	English
Published:	Wolters Kluwer Health 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442012/

id	pubmed-4442012
recordtype	oai_dc
spelling	pubmed-44420122015-05-24 Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA) Marsh, Elisabeth B. Gottesman, Rebecca F. Hillis, Argye E. Urrutia, Victor C. Llinas, Rafael H. Original Study Symptomatic intracranial hemorrhage (sICH) is a known complication following administration of intravenous tissue plasminogen activator (IV tPA) for acute ischemic stroke. sICH results in high rates of death or long-term disability. Our ability to predict its occurrence is important in clinical decision making and when counseling families. The initial National Institute of Neurological Disorders and Stroke (NINDS) investigators developed a list of relative contraindications to IV tPA meant to decrease the risk of subsequent sICH. To date, the impact of renal impairment has not been well studied. In the current study we evaluate the potential association between renal impairment and post-tPA intracranial hemorrhage (ICH). Wolters Kluwer Health 2013-11 2013-11-14 /pmc/articles/PMC4442012/ /pubmed/24145699 http://dx.doi.org/10.1097/MD.0000000000000006 Text en Copyright © 2013 by Lippincott Williams & Wilkins
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Marsh, Elisabeth B. Gottesman, Rebecca F. Hillis, Argye E. Urrutia, Victor C. Llinas, Rafael H.
spellingShingle	Marsh, Elisabeth B. Gottesman, Rebecca F. Hillis, Argye E. Urrutia, Victor C. Llinas, Rafael H. Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)
author_facet	Marsh, Elisabeth B. Gottesman, Rebecca F. Hillis, Argye E. Urrutia, Victor C. Llinas, Rafael H.
author_sort	Marsh, Elisabeth B.
title	Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)
title_short	Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)
title_full	Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)
title_fullStr	Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)
title_full_unstemmed	Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)
title_sort	serum creatinine may indicate risk of symptomatic intracranial hemorrhage after intravenous tissue plasminogen activator (iv tpa)
description	Symptomatic intracranial hemorrhage (sICH) is a known complication following administration of intravenous tissue plasminogen activator (IV tPA) for acute ischemic stroke. sICH results in high rates of death or long-term disability. Our ability to predict its occurrence is important in clinical decision making and when counseling families. The initial National Institute of Neurological Disorders and Stroke (NINDS) investigators developed a list of relative contraindications to IV tPA meant to decrease the risk of subsequent sICH. To date, the impact of renal impairment has not been well studied. In the current study we evaluate the potential association between renal impairment and post-tPA intracranial hemorrhage (ICH).
publisher	Wolters Kluwer Health
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442012/
_version_	1613227146787946496

Serum Creatinine May Indicate Risk of Symptomatic Intracranial Hemorrhage After Intravenous Tissue Plasminogen Activator (IV tPA)

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