Synthesis of Regiospecifically Fluorinated Conjugated Dienamides

Modular synthesis of regiospecifically fluorinated 2,4-diene Weinreb amides, with defined stereochemistry at both double bonds, was achieved via two sequential Julia-Kocienski olefinations. In the first step, a Z-α-fluorovinyl Weinreb amide unit with a benzothiazolylsulfanyl substituent at the allyl...

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Bibliographic Details
Main Authors: Chowdhury, Mohammad, Mandal, Samir K., Banerjee, Shaibal, Zajc, Barbara
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440806/