IGFBP-5 Metabolism Is Disrupted in the Rat Medial Meniscal Tear Model of Osteoarthritis

IGFBP-5 Metabolism Is Disrupted in the Rat Medial Meniscal Tear Model of Osteoarthritis

Insulin-like growth factor binding protein 5 (IGFBP-5) has been proposed to promote cartilage anabolism through insulin-like growth factor (IGF-1) signaling. A proteolytic activity towards IGFBP-5 has been detected in synovial fluids from human osteoarthritic (OA) joints. The purpose of this study w...

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Bibliographic Details
Main Authors: Yates, Matthew P., Settle, Steven L., Yocum, Sue A., Aggarwal, Poonam, Vickery, Lillian E., Aguiar, Dean J., Skepner, Adam P., Kellner, Debra, Weinrich, Scott L., Sverdrup, Francis M.
Format: Online
Language:English
Published: SAGE Publications 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440612/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440612/

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