Electronic cigarettes and nicotine dependence: evolving products, evolving problems

Electronic cigarettes (ECIGs) use an electric heater to aerosolize a liquid that usually contains propylene glycol, vegetable glycerin, flavorants, and the dependence-producing drug nicotine. ECIG-induced nicotine dependence has become an important concern, as some ECIGs deliver very little nicotine...

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Main Authors:	Cobb, Caroline O, Hendricks, Peter S, Eissenberg, Thomas
Format:	Online
Language:	English
Published:	BioMed Central 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440602/

id	pubmed-4440602
recordtype	oai_dc
spelling	pubmed-44406022015-05-22 Electronic cigarettes and nicotine dependence: evolving products, evolving problems Cobb, Caroline O Hendricks, Peter S Eissenberg, Thomas Commentary Electronic cigarettes (ECIGs) use an electric heater to aerosolize a liquid that usually contains propylene glycol, vegetable glycerin, flavorants, and the dependence-producing drug nicotine. ECIG-induced nicotine dependence has become an important concern, as some ECIGs deliver very little nicotine while some may exceed the nicotine delivery profile of a tobacco cigarette. This variability is relevant to tobacco cigarette smokers who try to switch to ECIGs. Products with very low nicotine delivery may not substitute for tobacco cigarettes, so that ECIG use is accompanied by little reduced risk of cigarette-caused disease. Products with very high nicotine delivery may make quitting ECIGs particularly difficult should users decide to try. For non-smokers, the wide variability of ECIGs on the market is especially troublesome: low nicotine products may lead them to initiate nicotine self-administration and progress to higher dosing ECIGs or other products, and those that deliver more nicotine may produce nicotine dependence where it was not otherwise present. External regulatory action, guided by strong science, may be required to ensure that population-level nicotine dependence does not rise. BioMed Central 2015-05-21 /pmc/articles/PMC4440602/ /pubmed/25998379 http://dx.doi.org/10.1186/s12916-015-0355-y Text en © Cobb et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Cobb, Caroline O Hendricks, Peter S Eissenberg, Thomas
spellingShingle	Cobb, Caroline O Hendricks, Peter S Eissenberg, Thomas Electronic cigarettes and nicotine dependence: evolving products, evolving problems
author_facet	Cobb, Caroline O Hendricks, Peter S Eissenberg, Thomas
author_sort	Cobb, Caroline O
title	Electronic cigarettes and nicotine dependence: evolving products, evolving problems
title_short	Electronic cigarettes and nicotine dependence: evolving products, evolving problems
title_full	Electronic cigarettes and nicotine dependence: evolving products, evolving problems
title_fullStr	Electronic cigarettes and nicotine dependence: evolving products, evolving problems
title_full_unstemmed	Electronic cigarettes and nicotine dependence: evolving products, evolving problems
title_sort	electronic cigarettes and nicotine dependence: evolving products, evolving problems
description	Electronic cigarettes (ECIGs) use an electric heater to aerosolize a liquid that usually contains propylene glycol, vegetable glycerin, flavorants, and the dependence-producing drug nicotine. ECIG-induced nicotine dependence has become an important concern, as some ECIGs deliver very little nicotine while some may exceed the nicotine delivery profile of a tobacco cigarette. This variability is relevant to tobacco cigarette smokers who try to switch to ECIGs. Products with very low nicotine delivery may not substitute for tobacco cigarettes, so that ECIG use is accompanied by little reduced risk of cigarette-caused disease. Products with very high nicotine delivery may make quitting ECIGs particularly difficult should users decide to try. For non-smokers, the wide variability of ECIGs on the market is especially troublesome: low nicotine products may lead them to initiate nicotine self-administration and progress to higher dosing ECIGs or other products, and those that deliver more nicotine may produce nicotine dependence where it was not otherwise present. External regulatory action, guided by strong science, may be required to ensure that population-level nicotine dependence does not rise.
publisher	BioMed Central
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440602/
_version_	1613226685108322304

Electronic cigarettes and nicotine dependence: evolving products, evolving problems

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