The Oncogenic MicroRNA miR-21 Promotes Regulated Necrosis in Mice

The Oncogenic MicroRNA miR-21 Promotes Regulated Necrosis in Mice

MicroRNAs (miRNAs) regulate apoptosis, yet their role in regulated necrosis remains unknown. miR-21 is overexpressed in nearly all human cancer types and its role as an oncogene is suggested to largely depend on its anti-apoptotic action. Here we show that miR-21 is overexpressed in a murine model o...

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Bibliographic Details
Main Authors: Ma, Xiaodong, Conklin, Daniel J., Li, Fenge, Dai, Zhongping, Hua, Xiang, Li, Yan, Xu-Monette, Zijun Y., Young, Ken H., Xiong, Wei, Wysoczynski, Marcin, Sithu, Srinivas D., Srivastava, Sanjay, Bhatnagar, Aruni, Li, Yong
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440243/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440243/

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