Applying the ARRIVE Guidelines to an In Vivo Database
The Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines were developed to address the lack of reproducibility in biomedical animal studies and improve the communication of research findings. While intended to guide the preparation of peer-reviewed manuscripts, the principles of tra...
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| Format: | Online |
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Public Library of Science
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439173/ |
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pubmed-4439173 |
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pubmed-44391732015-05-29 Applying the ARRIVE Guidelines to an In Vivo Database Karp, Natasha A. Meehan, Terry F. Morgan, Hugh Mason, Jeremy C. Blake, Andrew Kurbatova, Natalja Smedley, Damian Jacobsen, Julius Mott, Richard F. Iyer, Vivek Matthews, Peter Melvin, David G. Wells, Sara Flenniken, Ann M. Masuya, Hiroshi Wakana, Shigeharu White, Jacqueline K. Lloyd, K. C. Kent Reynolds, Corey L. Paylor, Richard West, David B. Svenson, Karen L. Chesler, Elissa J. de Angelis, Martin Hrabě Tocchini-Valentini, Glauco P. Sorg, Tania Herault, Yann Parkinson, Helen Mallon, Ann-Marie Brown, Steve D. M. Community Page The Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines were developed to address the lack of reproducibility in biomedical animal studies and improve the communication of research findings. While intended to guide the preparation of peer-reviewed manuscripts, the principles of transparent reporting are also fundamental for in vivo databases. Here, we describe the benefits and challenges of applying the guidelines for the International Mouse Phenotyping Consortium (IMPC), whose goal is to produce and phenotype 20,000 knockout mouse strains in a reproducible manner across ten research centres. In addition to ensuring the transparency and reproducibility of the IMPC, the solutions to the challenges of applying the ARRIVE guidelines in the context of IMPC will provide a resource to help guide similar initiatives in the future. Public Library of Science 2015-05-20 /pmc/articles/PMC4439173/ /pubmed/25992600 http://dx.doi.org/10.1371/journal.pbio.1002151 Text en © 2015 Karp et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Karp, Natasha A. Meehan, Terry F. Morgan, Hugh Mason, Jeremy C. Blake, Andrew Kurbatova, Natalja Smedley, Damian Jacobsen, Julius Mott, Richard F. Iyer, Vivek Matthews, Peter Melvin, David G. Wells, Sara Flenniken, Ann M. Masuya, Hiroshi Wakana, Shigeharu White, Jacqueline K. Lloyd, K. C. Kent Reynolds, Corey L. Paylor, Richard West, David B. Svenson, Karen L. Chesler, Elissa J. de Angelis, Martin Hrabě Tocchini-Valentini, Glauco P. Sorg, Tania Herault, Yann Parkinson, Helen Mallon, Ann-Marie Brown, Steve D. M. |
| spellingShingle |
Karp, Natasha A. Meehan, Terry F. Morgan, Hugh Mason, Jeremy C. Blake, Andrew Kurbatova, Natalja Smedley, Damian Jacobsen, Julius Mott, Richard F. Iyer, Vivek Matthews, Peter Melvin, David G. Wells, Sara Flenniken, Ann M. Masuya, Hiroshi Wakana, Shigeharu White, Jacqueline K. Lloyd, K. C. Kent Reynolds, Corey L. Paylor, Richard West, David B. Svenson, Karen L. Chesler, Elissa J. de Angelis, Martin Hrabě Tocchini-Valentini, Glauco P. Sorg, Tania Herault, Yann Parkinson, Helen Mallon, Ann-Marie Brown, Steve D. M. Applying the ARRIVE Guidelines to an In Vivo Database |
| author_facet |
Karp, Natasha A. Meehan, Terry F. Morgan, Hugh Mason, Jeremy C. Blake, Andrew Kurbatova, Natalja Smedley, Damian Jacobsen, Julius Mott, Richard F. Iyer, Vivek Matthews, Peter Melvin, David G. Wells, Sara Flenniken, Ann M. Masuya, Hiroshi Wakana, Shigeharu White, Jacqueline K. Lloyd, K. C. Kent Reynolds, Corey L. Paylor, Richard West, David B. Svenson, Karen L. Chesler, Elissa J. de Angelis, Martin Hrabě Tocchini-Valentini, Glauco P. Sorg, Tania Herault, Yann Parkinson, Helen Mallon, Ann-Marie Brown, Steve D. M. |
| author_sort |
Karp, Natasha A. |
| title |
Applying the ARRIVE Guidelines to an In Vivo Database |
| title_short |
Applying the ARRIVE Guidelines to an In Vivo Database |
| title_full |
Applying the ARRIVE Guidelines to an In Vivo Database |
| title_fullStr |
Applying the ARRIVE Guidelines to an In Vivo Database |
| title_full_unstemmed |
Applying the ARRIVE Guidelines to an In Vivo Database |
| title_sort |
applying the arrive guidelines to an in vivo database |
| description |
The Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines were developed to address the lack of reproducibility in biomedical animal studies and improve the communication of research findings. While intended to guide the preparation of peer-reviewed manuscripts, the principles of transparent reporting are also fundamental for in vivo databases. Here, we describe the benefits and challenges of applying the guidelines for the International Mouse Phenotyping Consortium (IMPC), whose goal is to produce and phenotype 20,000 knockout mouse strains in a reproducible manner across ten research centres. In addition to ensuring the transparency and reproducibility of the IMPC, the solutions to the challenges of applying the ARRIVE guidelines in the context of IMPC will provide a resource to help guide similar initiatives in the future. |
| publisher |
Public Library of Science |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439173/ |
| _version_ |
1613226192904650752 |