Elimination of Tumorigenic Human Pluripotent Stem Cells by a Recombinant Lectin-Toxin Fusion Protein

The application of stem-cell-based therapies in regenerative medicine is hindered by the tumorigenic potential of residual human pluripotent stem cells. Previously, we identified a human pluripotent stem-cell-specific lectin probe, called rBC2LCN, by comprehensive glycome analysis using high-density...

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Bibliographic Details
Main Authors: Tateno, Hiroaki, Onuma, Yasuko, Ito, Yuzuru, Minoshima, Fumi, Saito, Sayoko, Shimizu, Madoka, Aiki, Yasuhiko, Asashima, Makoto, Hirabayashi, Jun
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437484/