Structure of Slitrk2–PTPδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion

Structure of Slitrk2–PTPδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion

Selective binding between pre- and postsynaptic adhesion molecules can induce synaptic differentiation. Here we report the crystal structure of a synaptogenic trans-synaptic adhesion complex between Slit and Trk-like family member 2 (Slitrk2) and receptor protein tyrosine phosphatase (RPTP) δ. The s...

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Bibliographic Details
Main Authors: Yamagata, Atsushi, Sato, Yusuke, Goto-Ito, Sakurako, Uemura, Takeshi, Maeda, Asami, Shiroshima, Tomoko, Yoshida, Tomoyuki, Fukai, Shuya
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437028/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437028/

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