Quantitative intravital two-photon excitation microscopy reveals absence of pulmonary vaso-occlusion in unchallenged Sickle Cell Disease mice
Sickle cell disease (SCD) is a genetic disorder that leads to red blood cell (RBC) sickling, hemolysis and the upregulation of adhesion molecules on sickle RBCs. Chronic hemolysis in SCD results in a hyper-inflammatory state characterized by activation of circulating leukocytes, platelets and endoth...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Taylor & Francis
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435611/ |