Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy
The development of robust nonviral vectors could facilitate clinical gene therapy applications and may overcome some of the immune complications of viral vectors. Nevertheless, most nonviral gene deliver approaches typically yield only transient and/or low gene expression. To address these caveats,...
Main Authors: | , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435487/ |