Delivery of microRNA-146a with polyethylenimine nanoparticles inhibits renal fibrosis in vivo

Renal fibrosis is the final common pathway leading to end-stage renal disease. Although microRNA (miR) was recently shown to be involved in the development of renal fibrosis, few studies have focused on the effects on renal fibrosis of exogenous miR delivered in an in vivo therapeutic setting. The s...

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Bibliographic Details
Main Authors: Morishita, Yoshiyuki, Imai, Toshimi, Yoshizawa, Hiromichi, Watanabe, Minami, Ishibashi, Kenichi, Muto, Shigeaki, Nagata, Daisuke
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435251/