Characterization of two acetyltransferase genes in the pyripyropene biosynthetic gene cluster from Penicillium coprobium
Pyripyropenes potently and selectively inhibit acyl-CoA:cholesterol acyltransferase 2 (ACAT-2). Among multiple isomers of pyripyropene (A to R), pyripyropene A (PyA) has insecticidal properties in addition to its growth inhibition properties against human umbilical vein endothelial cells. Based on t...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Taylor & Francis
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434069/ |