Aerobic Glycolysis: Beyond Proliferation

Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review, we will discuss some recent findings to illustrate newly defined roles for this process, in par...

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Main Authors: Jones, William, Bianchi, Katiuscia
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432802/
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spelling pubmed-44328022015-05-29 Aerobic Glycolysis: Beyond Proliferation Jones, William Bianchi, Katiuscia Immunology Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review, we will discuss some recent findings to illustrate newly defined roles for this process, in particular in non-malignant cells, supporting the idea that metabolism can be considered as an integral part of cellular signaling. Consequently, metabolism should be regarded as a plastic and highly dynamic determinant of a wide range of cellular specific functions. Frontiers Media S.A. 2015-05-15 /pmc/articles/PMC4432802/ /pubmed/26029212 http://dx.doi.org/10.3389/fimmu.2015.00227 Text en Copyright © 2015 Jones and Bianchi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Jones, William
Bianchi, Katiuscia
spellingShingle Jones, William
Bianchi, Katiuscia
Aerobic Glycolysis: Beyond Proliferation
author_facet Jones, William
Bianchi, Katiuscia
author_sort Jones, William
title Aerobic Glycolysis: Beyond Proliferation
title_short Aerobic Glycolysis: Beyond Proliferation
title_full Aerobic Glycolysis: Beyond Proliferation
title_fullStr Aerobic Glycolysis: Beyond Proliferation
title_full_unstemmed Aerobic Glycolysis: Beyond Proliferation
title_sort aerobic glycolysis: beyond proliferation
description Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review, we will discuss some recent findings to illustrate newly defined roles for this process, in particular in non-malignant cells, supporting the idea that metabolism can be considered as an integral part of cellular signaling. Consequently, metabolism should be regarded as a plastic and highly dynamic determinant of a wide range of cellular specific functions.
publisher Frontiers Media S.A.
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432802/
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