Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

It is well accepted that aging and HIV infection are associated with quantitative and functional changes of CMV-specific T cell responses. We studied here the expression of Mip-1β and the T cell maturation marker CD27 within CMVpp65-specific CD4+ and CD8+ T cells in relation to age, HIV and active T...

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Main Authors: Portevin, Damien, Moukambi, Félicien, Mpina, Maxmillian, Bauer, Asli, Haraka, Frederick, Chachage, Mkunde, Metzger, Philipp, Saathoff, Elmar, Clowes, Petra, Ntinginya, Nyanda E., Rachow, Andrea, Hoelscher, Michael, Reither, Klaus, Daubenberger, Claudia A., Geldmacher, Christof
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431818/

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