Early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer

•The conventional clinicopathological factors are limited to predict the outcomes in bladder cancer.•Combination of cellular regulatory markers has been demonstrated to improve the accuracy of prediction.•This case is an unexpected case of NMIBC developed early and isolated bone metastases following...

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Main Author: Hong, Jeong Hee
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429853/
id pubmed-4429853
recordtype oai_dc
spelling pubmed-44298532015-05-15 Early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer Hong, Jeong Hee Case Report •The conventional clinicopathological factors are limited to predict the outcomes in bladder cancer.•Combination of cellular regulatory markers has been demonstrated to improve the accuracy of prediction.•This case is an unexpected case of NMIBC developed early and isolated bone metastases following surgery.•The altered expressions of combined cellular biomarkers, p53, Ki-67, and EGFR, were observed diffusely and intensively in the all specimens. Elsevier 2015-03-18 /pmc/articles/PMC4429853/ /pubmed/25799961 http://dx.doi.org/10.1016/j.ijscr.2015.03.029 Text en © 2015 The Author http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Hong, Jeong Hee
spellingShingle Hong, Jeong Hee
Early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer
author_facet Hong, Jeong Hee
author_sort Hong, Jeong Hee
title Early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer
title_short Early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer
title_full Early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer
title_fullStr Early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer
title_full_unstemmed Early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer
title_sort early isolated bone metastases without local recurrence in non-muscle invasive bladder cancer
description •The conventional clinicopathological factors are limited to predict the outcomes in bladder cancer.•Combination of cellular regulatory markers has been demonstrated to improve the accuracy of prediction.•This case is an unexpected case of NMIBC developed early and isolated bone metastases following surgery.•The altered expressions of combined cellular biomarkers, p53, Ki-67, and EGFR, were observed diffusely and intensively in the all specimens.
publisher Elsevier
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429853/
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