Dual HER2 blockade: preclinical and clinical data

The estrogen receptor and human epidermal growth factor receptor (HER) signaling pathways are the dominant drivers of cell proliferation and survival in the majority of human breast cancers. Not surprisingly, targeting these pathways provides the most effective therapies in appropriately selected pa...

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Bibliographic Details
Main Authors: Patel, Tejal A, Dave, Bhuvanesh, Rodriguez, Angel A, Chang, Jenny C, Perez, Edith A, Colon-Otero, Gerardo
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429364/