The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample

Sleep-disordered breathing (SDB), characterized by abnormal respiratory patterns or inadequate quantity of ventilation, is common in adults. A positive association between SDB and hypertension has been established, in both cross-sectional and longitudinal studies. One void in the literature concerns...

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Main Authors:	Geiger, Sarah Dee, Shankar, Anoop
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429187/

id	pubmed-4429187
recordtype	oai_dc
spelling	pubmed-44291872015-06-10 The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample Geiger, Sarah Dee Shankar, Anoop Research Article Sleep-disordered breathing (SDB), characterized by abnormal respiratory patterns or inadequate quantity of ventilation, is common in adults. A positive association between SDB and hypertension has been established, in both cross-sectional and longitudinal studies. One void in the literature concerns the role of race/ethnicity in the association between SDB and hypertension. In this context, a cross-sectional study was performed on 6,783 participants in the National Health and Nutrition Examination Survey 2005–2008. Participants were ≥age 20 and free from cardiovascular disease. The outcome of interest was hypertension, defined as ≥140 mmHg systolic blood pressure (BP), and/or ≥90 mmHg diastolic BP or antihypertensive medication use. Self-reported SDB was positively associated with hypertension, independent of confounders such as depression, diabetes, cholesterol levels, and body mass index, among others. The association persisted in subgroup analyses by gender, with a stronger association among males than females, as well as by race/ethnicity, with non-Hispanic blacks displaying the strongest association. In the multivariable-adjusted model, compared to a sleep summary score of zero (referent), the OR (95% CI) of hypertension for non-Hispanic blacks was 1.34 (0.98–1.83) for a sleep summary score of 1, 1.44 (1.06–1.97) for a score of 2 and 3.72 (1.98–7.00) for a score of >3; p-trend < 0.0001. SDB was positively associated with hypertension in a large, nationally representative sample of US adults. Along with being prevalent, SDB is also treatable. Therefore, our results are important for minority race/ethnic groups who typically experience a higher baseline for negative health outcomes. Hindawi Publishing Corporation 2015 2015-04-29 /pmc/articles/PMC4429187/ /pubmed/26064690 http://dx.doi.org/10.1155/2015/769798 Text en Copyright © 2015 S. D. Geiger and A. Shankar. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Geiger, Sarah Dee Shankar, Anoop
spellingShingle	Geiger, Sarah Dee Shankar, Anoop The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample
author_facet	Geiger, Sarah Dee Shankar, Anoop
author_sort	Geiger, Sarah Dee
title	The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample
title_short	The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample
title_full	The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample
title_fullStr	The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample
title_full_unstemmed	The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample
title_sort	relationship between sleep-disordered breathing and hypertension in a nationally representative sample
description	Sleep-disordered breathing (SDB), characterized by abnormal respiratory patterns or inadequate quantity of ventilation, is common in adults. A positive association between SDB and hypertension has been established, in both cross-sectional and longitudinal studies. One void in the literature concerns the role of race/ethnicity in the association between SDB and hypertension. In this context, a cross-sectional study was performed on 6,783 participants in the National Health and Nutrition Examination Survey 2005–2008. Participants were ≥age 20 and free from cardiovascular disease. The outcome of interest was hypertension, defined as ≥140 mmHg systolic blood pressure (BP), and/or ≥90 mmHg diastolic BP or antihypertensive medication use. Self-reported SDB was positively associated with hypertension, independent of confounders such as depression, diabetes, cholesterol levels, and body mass index, among others. The association persisted in subgroup analyses by gender, with a stronger association among males than females, as well as by race/ethnicity, with non-Hispanic blacks displaying the strongest association. In the multivariable-adjusted model, compared to a sleep summary score of zero (referent), the OR (95% CI) of hypertension for non-Hispanic blacks was 1.34 (0.98–1.83) for a sleep summary score of 1, 1.44 (1.06–1.97) for a score of 2 and 3.72 (1.98–7.00) for a score of >3; p-trend < 0.0001. SDB was positively associated with hypertension in a large, nationally representative sample of US adults. Along with being prevalent, SDB is also treatable. Therefore, our results are important for minority race/ethnic groups who typically experience a higher baseline for negative health outcomes.
publisher	Hindawi Publishing Corporation
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429187/
_version_	1613222555882094592

The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample

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