DNA repair mechanisms and human cytomegalovirus (HCMV) infection
Herpesvirus infections, such as those induced by human cytomegalovirus (HCMV), induce specific DNA damages. DNA damages can lead to cell mutation, death, apoptosis and immune system activation. Various types of DNA damage are repaired through multiple repair pathways, such as base excision, nucleoti...
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| Format: | Online |
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Springer Netherlands
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429022/ |
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pubmed-44290222015-05-18 DNA repair mechanisms and human cytomegalovirus (HCMV) infection Smolarz, Beata Wilczyński, Jan Nowakowska, Dorota Article Herpesvirus infections, such as those induced by human cytomegalovirus (HCMV), induce specific DNA damages. DNA damages can lead to cell mutation, death, apoptosis and immune system activation. Various types of DNA damage are repaired through multiple repair pathways, such as base excision, nucleotide excision, homologous recombination and nonhomologous end joining. Changes in the activity of DNA repair proteins during viral infection can cause disturbances in the DNA repair system and change its mechanisms. This report reviews results from studies, assaying a DNA repair system in HCMV infection. Springer Netherlands 2014-11-01 2015 /pmc/articles/PMC4429022/ /pubmed/25366712 http://dx.doi.org/10.1007/s12223-014-0359-6 Text en © The Author(s) 2014 Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Smolarz, Beata Wilczyński, Jan Nowakowska, Dorota |
| spellingShingle |
Smolarz, Beata Wilczyński, Jan Nowakowska, Dorota DNA repair mechanisms and human cytomegalovirus (HCMV) infection |
| author_facet |
Smolarz, Beata Wilczyński, Jan Nowakowska, Dorota |
| author_sort |
Smolarz, Beata |
| title |
DNA repair mechanisms and human cytomegalovirus (HCMV) infection |
| title_short |
DNA repair mechanisms and human cytomegalovirus (HCMV) infection |
| title_full |
DNA repair mechanisms and human cytomegalovirus (HCMV) infection |
| title_fullStr |
DNA repair mechanisms and human cytomegalovirus (HCMV) infection |
| title_full_unstemmed |
DNA repair mechanisms and human cytomegalovirus (HCMV) infection |
| title_sort |
dna repair mechanisms and human cytomegalovirus (hcmv) infection |
| description |
Herpesvirus infections, such as those induced by human cytomegalovirus (HCMV), induce specific DNA damages. DNA damages can lead to cell mutation, death, apoptosis and immune system activation. Various types of DNA damage are repaired through multiple repair pathways, such as base excision, nucleotide excision, homologous recombination and nonhomologous end joining. Changes in the activity of DNA repair proteins during viral infection can cause disturbances in the DNA repair system and change its mechanisms. This report reviews results from studies, assaying a DNA repair system in HCMV infection. |
| publisher |
Springer Netherlands |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429022/ |
| _version_ |
1613222484265402368 |