Two-pore domain potassium channels enable action potential generation in the absence of voltage-gated potassium channels

In this study, we explored the possibility that two-pore domain potassium (K2P) channels are sufficient to support action potential (AP) generation in the absence of conventional voltage-gated potassium (KV) channels. Hodgkin–Huxley parameters were used to mimic the presence of voltage-gated sodium...

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Bibliographic Details
Main Authors: MacKenzie, Georgina, Franks, Nicholas P., Brickley, Stephen G.
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428809/