The synaptotagmin juxtamembrane domain is involved in neuroexocytosis

•The highly cationic juxtamembrane segment of synaptotagmin juxtamembrane domain was synthesized.•This peptide inhibits neurotransmitter release at the neuromuscular junction of mice and Drosophila.•This peptide localizes mainly on the presynaptic membrane.•The synaptotagmin juxtamembrane peptide bi...

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Bibliographic Details
Main Authors: Caccin, Paola, Scorzeto, Michele, Damiano, Nunzio, Marin, Oriano, Megighian, Aram, Montecucco, Cesare
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427626/