PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens

ΔFosB is a stable transcription factor which accumulates in the nucleus accumbens (NAc), a key part of the brain’s reward circuitry, in response to chronic exposure to cocaine or other drugs of abuse. While ΔFosB is known to heterodimerize with a Jun family member to form an active transcription fac...

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Bibliographic Details
Main Authors: Ohnishi, Yoko H., Ohnishi, Yoshinori N., Nakamura, Takanori, Ohno, Mizuki, Kennedy, Pamela J., Yasuyuki, Ohkawa, Nishi, Akinori, Neve, Rachael, Tsuzuki, Teruhisa, Nestler, Eric J.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427335/