Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy

Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy

The transgenic E1-DN mice express a kinase-negative epidermal growth factor receptor in their pancreatic islets and are diabetic from two weeks of age due to impaired postnatal growth of β-cell mass. Here, we characterize the development of hyperglycaemia-induced renal injury in the E1-DN mice. Homo...

Full description

Bibliographic Details
Main Authors: Hyvönen, Mervi E., Dumont, Vincent, Tienari, Jukka, Lehtonen, Eero, Ustinov, Jarkko, Havana, Marika, Jalanko, Hannu, Otonkoski, Timo, Miettinen, Päivi J., Lehtonen, Sanna
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426768/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426768/

Similar Items