Identification of Variants in Primary and Recurrent Glioblastoma Using a Cancer-Specific Gene Panel and Whole Exome Sequencing
Glioblastoma (GBM) is an aggressive, malignant brain tumor typically resulting in death of the patient within one year following diagnosis; and those who survive beyond this point usually present with tumor recurrence within two years (5-year survival is 5%). The genetic heterogeneity of GBM has mad...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423782/ |