Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon

An endometrial stromal sarcoma (ESS) is an uncommon uterine neoplasm, and its primary occurrence in the intestine as an extrauterine ESS (EESS) is exceedingly rare. We hereby report a primary EESS arising in the sigmoid colon with a review of the literature. A 52-year-old woman presented with bloody...

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Main Authors:	Son, Hyun-Jin, Kim, Joo-Heon, Kang, Dong-Wook, Lee, Hye-Kyung, Park, Mee-Ja, Lee, Seung Yun
Format:	Online
Language:	English
Published:	The Korean Society of Coloproctology 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422990/

id	pubmed-4422990
recordtype	oai_dc
spelling	pubmed-44229902015-05-08 Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon Son, Hyun-Jin Kim, Joo-Heon Kang, Dong-Wook Lee, Hye-Kyung Park, Mee-Ja Lee, Seung Yun Case Report An endometrial stromal sarcoma (ESS) is an uncommon uterine neoplasm, and its primary occurrence in the intestine as an extrauterine ESS (EESS) is exceedingly rare. We hereby report a primary EESS arising in the sigmoid colon with a review of the literature. A 52-year-old woman presented with bloody stool and underwent a colon fiberscopy, which revealed a fungating mass obstructing the lumen at the distal sigmoid. A laparoscopic low anterior resection was performed, and an umbilicated polypoid mass was identified; on section, it had infiltrated the mesocolic fat and measured 3.8 cm × 2.5 cm. The tumor showed geographic sheets or nests composed of relatively monotonous stromal cells, expansion or infiltration to the proper muscle and mesocolic fat, and extensive lymphovascular invasion and metastasis to regional lymph nodes and the pelvic peritoneum. The tumor cells were strongly and diffusely immunoreactive for CD10, but negative for c-kit, CD34, and Dog1. Two months later, a hysterectomy with a bilateral salpingo-oophorectomy was performed, and no evidence of an ESS was found in the uterus. The Korean Society of Coloproctology 2015-04 2015-04-30 /pmc/articles/PMC4422990/ /pubmed/25960975 http://dx.doi.org/10.3393/ac.2015.31.2.68 Text en © 2015 The Korean Society of Coloproctology http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Son, Hyun-Jin Kim, Joo-Heon Kang, Dong-Wook Lee, Hye-Kyung Park, Mee-Ja Lee, Seung Yun
spellingShingle	Son, Hyun-Jin Kim, Joo-Heon Kang, Dong-Wook Lee, Hye-Kyung Park, Mee-Ja Lee, Seung Yun Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon
author_facet	Son, Hyun-Jin Kim, Joo-Heon Kang, Dong-Wook Lee, Hye-Kyung Park, Mee-Ja Lee, Seung Yun
author_sort	Son, Hyun-Jin
title	Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon
title_short	Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon
title_full	Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon
title_fullStr	Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon
title_full_unstemmed	Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon
title_sort	primary extrauterine endometrial stromal sarcoma in the sigmoid colon
description	An endometrial stromal sarcoma (ESS) is an uncommon uterine neoplasm, and its primary occurrence in the intestine as an extrauterine ESS (EESS) is exceedingly rare. We hereby report a primary EESS arising in the sigmoid colon with a review of the literature. A 52-year-old woman presented with bloody stool and underwent a colon fiberscopy, which revealed a fungating mass obstructing the lumen at the distal sigmoid. A laparoscopic low anterior resection was performed, and an umbilicated polypoid mass was identified; on section, it had infiltrated the mesocolic fat and measured 3.8 cm × 2.5 cm. The tumor showed geographic sheets or nests composed of relatively monotonous stromal cells, expansion or infiltration to the proper muscle and mesocolic fat, and extensive lymphovascular invasion and metastasis to regional lymph nodes and the pelvic peritoneum. The tumor cells were strongly and diffusely immunoreactive for CD10, but negative for c-kit, CD34, and Dog1. Two months later, a hysterectomy with a bilateral salpingo-oophorectomy was performed, and no evidence of an ESS was found in the uterus.
publisher	The Korean Society of Coloproctology
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422990/
_version_	1613220418096726016

Primary Extrauterine Endometrial Stromal Sarcoma in the Sigmoid Colon

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