Integrative network analysis reveals molecular mechanisms of blood pressure regulation

Genome-wide association studies (GWAS) have identified numerous loci associated with blood pressure (BP). The molecular mechanisms underlying BP regulation, however, remain unclear. We investigated BP-associated molecular mechanisms by integrating BP GWAS with whole blood mRNA expression profiles in...

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Bibliographic Details
Main Authors: Huan, Tianxiao, Meng, Qingying, Saleh, Mohamed A, Norlander, Allison E, Joehanes, Roby, Zhu, Jun, Chen, Brian H, Zhang, Bin, Johnson, Andrew D, Ying, Saixia, Courchesne, Paul, Raghavachari, Nalini, Wang, Richard, Liu, Poching, O'Donnell, Christopher J, Vasan, Ramachandran, Munson, Peter J, Madhur, Meena S, Harrison, David G, Yang, Xia, Levy, Daniel
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422556/