Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection

A renal biopsy was performed in a 47-year-old man with haemophilia A. Thirty minutes after administration of an intravenous bolus of 4000 units of recombinant factor VIII, which increased the activity to 74–91%, a needle renal biopsy was successfully performed, followed by administration of 3000 uni...

Full description

Bibliographic Details
Main Authors:	Kobayashi, Ikue, Ishimura, Eiji, Hirowatari, Kaname, Tsuchida, Takao, Nishihira, Ayako, Shima, Hideaki, Shidara, Kaori, Mori, Katsuhito, Inaba, Masaaki, Wakasa, Ken-ichi, Nishizawa, Yoshiki
Format:	Online
Language:	English
Published:	Oxford University Press 2009
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421390/

id	pubmed-4421390
recordtype	oai_dc
spelling	pubmed-44213902015-05-06 Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection Kobayashi, Ikue Ishimura, Eiji Hirowatari, Kaname Tsuchida, Takao Nishihira, Ayako Shima, Hideaki Shidara, Kaori Mori, Katsuhito Inaba, Masaaki Wakasa, Ken-ichi Nishizawa, Yoshiki Case Report A renal biopsy was performed in a 47-year-old man with haemophilia A. Thirty minutes after administration of an intravenous bolus of 4000 units of recombinant factor VIII, which increased the activity to 74–91%, a needle renal biopsy was successfully performed, followed by administration of 3000 units of factor VIII in the evening, and then the subsequent morning and evening. The patient was diagnosed with hepatitis C virus-associated membranoproliferative glomerulonephritis. Treatment with interferon, ribavirin, prednisolone and cyclosporine A improved the nephrotic syndrome. This is the first report of a successful renal biopsy in a patient with haemophilia A after factor VIII injection. Oxford University Press 2009-10 2009-06-22 /pmc/articles/PMC4421390/ /pubmed/25949347 http://dx.doi.org/10.1093/ndtplus/sfp072 Text en © The Author [2009]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Kobayashi, Ikue Ishimura, Eiji Hirowatari, Kaname Tsuchida, Takao Nishihira, Ayako Shima, Hideaki Shidara, Kaori Mori, Katsuhito Inaba, Masaaki Wakasa, Ken-ichi Nishizawa, Yoshiki
spellingShingle	Kobayashi, Ikue Ishimura, Eiji Hirowatari, Kaname Tsuchida, Takao Nishihira, Ayako Shima, Hideaki Shidara, Kaori Mori, Katsuhito Inaba, Masaaki Wakasa, Ken-ichi Nishizawa, Yoshiki Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection
author_facet	Kobayashi, Ikue Ishimura, Eiji Hirowatari, Kaname Tsuchida, Takao Nishihira, Ayako Shima, Hideaki Shidara, Kaori Mori, Katsuhito Inaba, Masaaki Wakasa, Ken-ichi Nishizawa, Yoshiki
author_sort	Kobayashi, Ikue
title	Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection
title_short	Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection
title_full	Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection
title_fullStr	Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection
title_full_unstemmed	Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection
title_sort	renal biopsy in a patient with haemophilia a and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis c virus infection
description	A renal biopsy was performed in a 47-year-old man with haemophilia A. Thirty minutes after administration of an intravenous bolus of 4000 units of recombinant factor VIII, which increased the activity to 74–91%, a needle renal biopsy was successfully performed, followed by administration of 3000 units of factor VIII in the evening, and then the subsequent morning and evening. The patient was diagnosed with hepatitis C virus-associated membranoproliferative glomerulonephritis. Treatment with interferon, ribavirin, prednisolone and cyclosporine A improved the nephrotic syndrome. This is the first report of a successful renal biopsy in a patient with haemophilia A after factor VIII injection.
publisher	Oxford University Press
publishDate	2009
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421390/
_version_	1613219740862382080

Renal biopsy in a patient with haemophilia A and cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection

Similar Items