The Role of the Calcium-Sensing Receptor in the Pathophysiology of Secondary Hyperparathyroidism

The calcium-sensing receptor (CaR), a seven-transmembrane domain receptor belonging to the G protein-coupled receptor family, is responsible for calcium-mediated signalling initiated at the surface of parathyroid cells that controls the synthesis and secretion of parathyroid hormone (PTH). Expressio...

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Bibliographic Details
Main Authors: Riccardi, Daniela, Martin, David
Format: Online
Language:English
Published: Oxford University Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421157/