The Role of the Calcium-Sensing Receptor in the Pathophysiology of Secondary Hyperparathyroidism
The calcium-sensing receptor (CaR), a seven-transmembrane domain receptor belonging to the G protein-coupled receptor family, is responsible for calcium-mediated signalling initiated at the surface of parathyroid cells that controls the synthesis and secretion of parathyroid hormone (PTH). Expressio...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2008
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421157/ |