8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction

8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction

Small molecule nonpeptidic mimics of α-helices are widely recognised as protein-protein interaction (PPIs) inhibitors. Protein-protein interactions mediate virtually all important regulatory pathways in a cell, and the ability to control and modulate PPIs is therefore of great significance to basic...

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Bibliographic Details
Main Authors: Pettersson, Mariell, Bliman, David, Jacobsson, Jimmy, Nilsson, Jesper R., Min, Jaeki, Iconaru, Luigi, Guy, R. Kiplin, Kriwacki, Richard W., Andréasson, Joakim, Grøtli, Morten
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420247/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420247/

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