An anti-silencer– and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development

An anti-silencer– and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development

Hao et al. report that a distant anti-silencer element interacts with the Rag1 and Rag2 gene promoters in double-positive thymocytes and that SATB1 is a regulator of Rag locus organization in these cells.

Bibliographic Details
Main Authors: Hao, Bingtao, Naik, Abani Kanta, Watanabe, Akiko, Tanaka, Hirokazu, Chen, Liang, Richards, Hunter W., Kondo, Motonari, Taniuchi, Ichiro, Kohwi, Yoshinori, Kohwi-Shigematsu, Terumi, Krangel, Michael S.
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419350/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419350/

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