Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow

Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow

Osteocalcin (Ocn)-expressing bone marrow cells produce the Notch ligand DLL4, and this is required for lymphoid progenitor cells to seed the thymus.

Bibliographic Details
Main Authors: Yu, Vionnie W.C., Saez, Borja, Cook, Colleen, Lotinun, Sutada, Pardo-Saganta, Ana, Wang, Ying-Hua, Lymperi, Stefania, Ferraro, Francesca, Raaijmakers, Marc H.G.P., Wu, Joy Y., Zhou, Lan, Rajagopal, Jayaraj, Kronenberg, Henry M., Baron, Roland, Scadden, David T.
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419348/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419348/

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