Alveolar macrophage–derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes

Alveolar macrophage–derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes

Goritzka et al. describe a role for recruited inflammatory monocytes in antiviral immunity and protection from RSV infection in mice. The authors demonstrate that this is critically dependent on the production of type I IFNs by alveolar macrophages triggered via RIG-I–like receptors, thus highlighti...

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Bibliographic Details
Main Authors: Goritzka, Michelle, Makris, Spyridon, Kausar, Fahima, Durant, Lydia R., Pereira, Catherine, Kumagai, Yutaro, Culley, Fiona J., Mack, Matthias, Akira, Shizuo, Johansson, Cecilia
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419339/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419339/

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