Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is the most common form of dementia, characterized by progressive neurodegeneration. Pathogenetic mechanisms, triggered by β-amyloid (Aβ) accumulation, include oxidative stress, derived from energy homeostasis deregulation and involving mitochondria and peroxisomes. We...

Full description

Bibliographic Details
Main Authors: Porcellotti, Sara, Fanelli, Francesca, Fracassi, Anna, Sepe, Sara, Cecconi, Francesco, Bernardi, Cinzia, Cimini, AnnaMaria, Cerù, Maria Paola, Moreno, Sandra
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418010/