CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

Genome editing tools such as the clustered regularly interspaced short palindromic repeat (CRISPR)-associated system (Cas) have been widely used to modify genes in model systems including animal zygotes and human cells, and hold tremendous promise for both basic research and clinical applications. T...

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Bibliographic Details
Main Authors: Liang, Puping, Xu, Yanwen, Zhang, Xiya, Ding, Chenhui, Huang, Rui, Zhang, Zhen, Lv, Jie, Xie, Xiaowei, Chen, Yuxi, Li, Yujing, Sun, Ying, Bai, Yaofu, Songyang, Zhou, Ma, Wenbin, Zhou, Canquan, Huang, Junjiu
Format: Online
Language:English
Published: Higher Education Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417674/