Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation
In a recent issue of Critical Care, Poole and colleagues found that plasma citrulline concentration and glucose absorption were reduced in 20 critically ill patients compared with 15 controls; however, the authors found no correlation between these two variables. This study highlights the question o...
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BioMed Central
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416254/ |
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pubmed-44162542015-05-02 Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation Piton, Gaël Capellier, Gilles Commentary In a recent issue of Critical Care, Poole and colleagues found that plasma citrulline concentration and glucose absorption were reduced in 20 critically ill patients compared with 15 controls; however, the authors found no correlation between these two variables. This study highlights the question of the accuracy of plasma citrulline for assessing small bowel function in critically ill patients. Future studies should take into account the type of intestinal failure considered, the particular metabolism of citrulline, the time of plasma citrulline measurement, as well as the range of citrullinemia considered. BioMed Central 2015-05-01 2015 /pmc/articles/PMC4416254/ /pubmed/25930068 http://dx.doi.org/10.1186/s13054-015-0881-1 Text en © Piton and Capellier; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Piton, Gaël Capellier, Gilles |
| spellingShingle |
Piton, Gaël Capellier, Gilles Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation |
| author_facet |
Piton, Gaël Capellier, Gilles |
| author_sort |
Piton, Gaël |
| title |
Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation |
| title_short |
Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation |
| title_full |
Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation |
| title_fullStr |
Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation |
| title_full_unstemmed |
Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation |
| title_sort |
plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation |
| description |
In a recent issue of Critical Care, Poole and colleagues found that plasma citrulline concentration and glucose absorption were reduced in 20 critically ill patients compared with 15 controls; however, the authors found no correlation between these two variables. This study highlights the question of the accuracy of plasma citrulline for assessing small bowel function in critically ill patients. Future studies should take into account the type of intestinal failure considered, the particular metabolism of citrulline, the time of plasma citrulline measurement, as well as the range of citrullinemia considered. |
| publisher |
BioMed Central |
| publishDate |
2015 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416254/ |
| _version_ |
1613218109121888256 |