5Z-7-Oxozeanol Inhibits the Effects of TGFβ1 on Human Gingival Fibroblasts

Transforming growth factor (TGF)β acts on fibroblasts to promote the production and remodeling of extracellular matrix (ECM). In adult humans, excessive action of TGFβ is associated with fibrotic disease and fibroproliferative conditions, including gingival hyperplasia. Understanding how the TGFβ1 s...

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Bibliographic Details
Main Authors: Kuk, Hanna, Hutchenreuther, James, Murphy-Marshman, Hannah, Carter, David, Leask, Andrew
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416036/