Argininosuccinate synthetase 1 suppression and arginine restriction inhibit cell migration in gastric cancer cell lines

Gastric cancer metastasis remains a major cause of cancer-related deaths. There is an urgent need to develop new therapeutic approaches targeting metastatic gastric cancer. Argininosuccinate synthetase 1 (ASS1) expression is increased in gastric cancer. We detected the protein expression of ASS1 in...

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Bibliographic Details
Main Authors: Shan, Yan-Shen, Hsu, Hui-Ping, Lai, Ming-Derg, Yen, Meng-Chi, Chen, Wei-Ching, Fang, Jung-Hua, Weng, Tzu-Yang, Chen, Yi-Ling
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415574/