Correcting for bias in the selection and validation of informative diagnostic tests

When developing a new diagnostic test for a disease, there are often multiple candidate classifiers to choose from, and it is unclear if any will offer an improvement in performance compared with current technology. A two-stage design can be used to select a promising classifier (if one exists) in s...

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Bibliographic Details
Main Authors: Robertson, David S, Prevost, A Toby, Bowden, Jack
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415464/