Neuronal activity biases axon selection for myelination in vivo

An essential feature of vertebrate neural development is ensheathment of axons with myelin, an insulating membrane formed by oligodendrocytes. Not all axons are myelinated, but mechanisms directing myelination of specific axons are unknown. Using zebrafish we show that activity-dependent secretion s...

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Bibliographic Details
Main Authors: Hines, Jacob H., Ravanelli, Andrew M., Schwindt, Rani, Scott, Ethan K., Appel, Bruce
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414883/