miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway

miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway

Increasing evidence suggests that miRNAs can act as either tumor suppressors or oncogenes in carcinogenesis. In the present study, we identified the role of miR-34a in regulating telomerase activity, with subsequent effect on cellular senescence and viability. We found the higher expression of miR-3...

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Bibliographic Details
Main Authors: Xu, Xinsen, Chen, Wei, Miao, Runchen, Zhou, Yanyan, Wang, Zhixin, Zhang, Lingqiang, Wan, Yong, Dong, Yafeng, Qu, Kai, Liu, Chang
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414168/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414168/

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