NF-κB signaling mediates acquired resistance after PARP inhibition

NF-κB signaling mediates acquired resistance after PARP inhibition

PARP inhibitors are a class of promising anti-cancer drugs, with proven activity in BRCA mutant cancers. However, as with other targeted agents, treatment with PARP inhibitors generates acquired resistance within these tumors. The mechanism of this acquired resistance is poorly understood. We establ...

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Bibliographic Details
Main Authors: Nakagawa, Yuko, Sedukhina, Anna S., Okamoto, Naoki, Nagasawa, Satoi, Suzuki, Nao, Ohta, Tomohiko, Hattori, Hiroyoshi, Roche-Molina, Marta, Narváez, Ana J., Jeyasekharan, Anand D., Bernal, Juan A., Sato, Ko
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414156/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414156/

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