The multiple cellular functions of the oncoprotein Golgi phosphoprotein 3

The highly conserved Golgi phosphoprotein 3 (GOLPH3) protein, a component of Trans-Golgi Network (TGN), has been defined as a “first-in-class Golgi oncoprotein” and characterized as a Phosphatidylinositol 4-phosphate [PI(4)P] effector at the Golgi. GOLPH3 is commonly amplified in several solid tumor...

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Bibliographic Details
Main Authors: Sechi, Stefano, Frappaolo, Anna, Belloni, Giorgio, Colotti, Gianni, Giansanti, Maria Grazia
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414131/