From sequence to structure and back again: approaches for predicting protein-DNA binding

Gene regulation in higher organisms is achieved by a complex network of transcription factors (TFs). Modulating gene expression and exploring gene function are major aims in molecular biology. Furthermore, the identification of putative target genes for a certain TF serve as powerful tools for speci...

Full description

Bibliographic Details
Main Authors: Höglund, Annette, Kohlbacher, Oliver
Format: Online
Language:English
Published: BioMed Central 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC441406/