Synthesis and in Vitro Antiproliferative Evaluation of Some B-norcholesteryl Benzimidazole and Benzothiazole Derivatives

Taking orostanal (a compound from a Japanese marine sponge, Stelletta hiwasaensis) as a lead compound, some novel B-norcholesteryl benzimidazole and benzothiazole derivatives were synthesized. The antiproliferative activity of the compounds against human cervical carcinoma (HeLa), human lung carcino...

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Bibliographic Details
Main Authors: Cui, Jianguo, Qi, Binbin, Gan, Chunfang, Liu, Zhipin, Huang, Hu, Lin, Qifu, Zhao, Dandan, Huang, Yanmin
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413222/