A Genome Wide Association Study Links Glutamate Receptor Pathway to Sporadic Creutzfeldt-Jakob Disease Risk

A Genome Wide Association Study Links Glutamate Receptor Pathway to Sporadic Creutzfeldt-Jakob Disease Risk

We performed a genome-wide association (GWA) study in 434 sporadic Creutzfeldt-Jakob disease (sCJD) patients and 1939 controls from the United Kingdom, Germany and The Netherlands. The findings were replicated in an independent sample of 1109 sCJD and 2264 controls provided by a multinational consor...

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Main Authors: Sanchez-Juan, Pascual, Bishop, Matthew T., Kovacs, Gabor G., Calero, Miguel, Aulchenko, Yurii S., Ladogana, Anna, Boyd, Alison, Lewis, Victoria, Ponto, Claudia, Calero, Olga, Poleggi, Anna, Carracedo, Ángel, van der Lee, Sven J., Ströbel, Thomas, Rivadeneira, Fernando, Hofman, Albert, Haïk, Stéphane, Combarros, Onofre, Berciano, José, Uitterlinden, Andre G., Collins, Steven J., Budka, Herbert, Brandel, Jean-Philippe, Laplanche, Jean Louis, Pocchiari, Maurizio, Zerr, Inga, Knight, Richard S. G., Will, Robert G., van Duijn, Cornelia M.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412535/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412535/

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