Broadening the repertoire of melanoma-associated T-cell epitopes

Immune therapy has provided a significant breakthrough in the treatment of metastatic melanoma. Despite the remarkable clinical efficacy and established involvement of effector CD8 T cells, the knowledge of the exact peptide-MHC complexes recognized by T cells on the tumor cell surface is limited. M...

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Bibliographic Details
Main Authors: Frøsig, Thomas Mørch, Lyngaa, Rikke, Met, Özcan, Larsen, Stine Kiær, Donia, Marco, Svane, Inge Marie, thor Straten, Per, Hadrup, Sine Reker
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412285/