CD200 Receptor Restriction of Myeloid Cell Responses Antagonizes Antiviral Immunity and Facilitates Cytomegalovirus Persistence within Mucosal Tissue

CD200 Receptor Restriction of Myeloid Cell Responses Antagonizes Antiviral Immunity and Facilitates Cytomegalovirus Persistence within Mucosal Tissue

CD200 receptor (CD200R) negatively regulates peripheral and mucosal innate immune responses. Viruses, including herpesviruses, have acquired functional CD200 orthologs, implying that viral exploitation of this pathway is evolutionary advantageous. However, the role that CD200R signaling plays during...

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Bibliographic Details
Main Authors: Stack, Gabrielle, Jones, Emma, Marsden, Morgan, Stacey, Maria A., Snelgrove, Robert J., Lacaze, Paul, Jacques, Laura C., Cuff, Simone M., Stanton, Richard J., Gallimore, Awen M., Hussell, Tracy, Wilkinson, Gavin W. G., Ghazal, Peter, Taylor, Philip R., Humphreys, Ian R.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412112/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412112/

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