Cyclic nucleotide binding and structural changes in the isolated GAF domain of Anabaena adenylyl cyclase, CyaB2

GAF domains are a large family of regulatory domains, and a subset are found associated with enzymes involved in cyclic nucleotide (cNMP) metabolism such as adenylyl cyclases and phosphodiesterases. CyaB2, an adenylyl cyclase from Anabaena, contains two GAF domains in tandem at the N-terminus and an...

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Bibliographic Details
Main Authors: Biswas, Kabir Hassan, Badireddy, Suguna, Rajendran, Abinaya, Anand, Ganesh Srinivasan, Visweswariah, Sandhya S.
Format: Online
Language:English
Published: PeerJ Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411481/