A STIM2 splice variant negatively regulates store-operated calcium entry

A STIM2 splice variant negatively regulates store-operated calcium entry

Cellular homeostasis relies upon precise regulation of Ca2+ concentration. Stromal interaction molecule (STIM) proteins regulate store-operated calcium entry (SOCE) by sensing Ca2+ concentration in the ER and forming oligomers to trigger Ca2+ entry through plasma membrane-localized Orai1 channels. H...

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Bibliographic Details
Main Authors: Miederer, Anna-Maria, Alansary, Dalia, Schwär, Gertrud, Lee, Po-Hsien, Jung, Martin, Helms, Volkhard, Niemeyer, Barbara A.
Format: Online
Language:English
Published: Nature Pub. Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411291/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411291/

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